There is a slim chance STALKER 2 will happen, as Sergey Grigorovich reopened GSC Gameworld in 2014, making Cossacks 3.
When asked about STALKER he said that it is a possibility provided GSC can make a successful (and profitiable) go of it again, giving them the resources to make a true STALKER sequel.
On the plus side Grigorovich resisted all attempts to take over the STALKER IP, I'm convinced he wants to do it right, if it is going to be done at all.
On the other negative side, most of the original STALKER devs have joined other companies in the time between GSC first shutting down and reopening.
When asked about STALKER he said that it is a possibility provided GSC can make a successful (and profitiable) go of it again, giving them the resources to make a true STALKER sequel.
On the plus side Grigorovich resisted all attempts to take over the STALKER IP, I'm convinced he wants to do it right, if it is going to be done at all.
On the other negative side, most of the original STALKER devs have joined other companies in the time between GSC first shutting down and reopening.