I ABXed 320kbit mp3 from an uncompressed original, I think 9/10 IIRC. It was a recording of castanets, and listening for frequency response differences was useless so I keyed off of 'personality' differences in the sounds and did it that way.
I was also just as horrible at detecting wow and flutter, as I was good at detecting lossy compression 'changes of sonic personality'. Comes from my experience being with analog audio, which is less true of people these days.
The idea that 'the best' listeners cannot tell 256k from even something as limited as 16/44.1 is ridiculous. Any mp3 format… any lossy format… is seriously compromised. Talk to techno/house DJs and producers about how useful it is to perform off mp3s, this is not a hypothetical argument.