Any library that's not on board needs to be wrapped, for sure. Fortunately you can do it in just the prototypes if you keep things ABI compatible. It fits well with the practice of decorating functions with empty structs, which is always ABI compatible (... in C, with mainstream compilers. In C++ it is explicitly not ABI compatible, sadly).
It's extra important, in writing this kind of C, to pick a granularity of types such that they help you make the distinctions you need without drowning you in casts. And I'm not at all sure such a granularity always exists. It worked out very well on the (greenfield) project I built this way, though.
Part of the problem then is that working with any standard library functions is a huge pain. You have to manually "cast" back and forth all the time.