If you're using a Logitech Receiver (small USB type A RF dongle [0]) plugged into a USB-C hub, interference might be causing your problems[1]. I used to have a setup like that, but after switching to Apple's USB-C adapters (USB-C to USB type A and/or USB-C to HDMI+USB type A) solved problems. Those adapters feature a short cable between the plug / ports, I wonder that's because of the interference?

[0]: https://www.logitech.com/en-us/product/unifying-receiver-usb [1]: https://www.intel.com/content/www/us/en/products/docs/io/uni...